|
Symbol Name ID |
Pparg
peroxisome proliferator activated receptor gamma MGI:97747 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypertrophic cardiomyopathy |
Coronary artery atherosclerosis |
Atherosclerosis |
Prominent superficial veins |
Prominent veins on trunk |
Elevated diastolic blood pressure |
Elevated systolic blood pressure |
Hypertension |
Congestive heart failure |
Abnormality of the hepatic vasculature |
Lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
| Disease(s) Associated with PPARG | |||||||||||||
| familial partial lipodystrophy type 3 | |||||||||||||
| pancreatic cancer | |||||||||||||
| pre-eclampsia |
| Mouse Phenotypes | abnormal pulmonary artery morphology |
abnormal retina vasculature morphology |
abnormal placental labyrinth vasculature morphology |
increased myocardial fiber size |
abnormal myocardial trabeculae morphology |
thin ventricle myocardium compact layer |
thin myocardium |
heart right ventricle hypertrophy |
abnormal heart development |
abnormal fetal cardiomyocyte morphology |
abnormal fetal cardiomyocyte mitochondrial morphology |
thin interventricular septum |
cardiac hypertrophy |
thin ventricular wall |
abnormal blood volume |
increased right ventricle systolic pressure |
decreased heart rate |
increased systemic arterial blood pressure |
hypertension |
increased mean systemic arterial blood pressure |
abnormal vascular endothelial cell physiology |
abnormal vasodilation |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Ppargtm1Rev/Ppargtm1Rev | |||||||||||||||||||||||
| Ppargtm1Tka/Ppargtm1Tka | |||||||||||||||||||||||
| Ppargtm1Lja/Pparg+ | |||||||||||||||||||||||
| Ppargtm1Mae/Pparg+ | |||||||||||||||||||||||
| Ppargtm1Rev/Ppargtm2Mae | |||||||||||||||||||||||
| Ppargtm1Tka/Pparg+ | |||||||||||||||||||||||
| Ppargtm1.1Gonz/Ppargtm1.1Gonz (conditional) | |||||||||||||||||||||||
| Ppargtm1.1Gonz/Ppargtm1.1Gonz Tg(Aqp2-cre)1Dek/0 (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Tek-cre)1Ywa/? (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Tek-cre)12Flv/? (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Tagln-cre)1Her/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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